The Hospital for Sick Children (SickKids) is Canada's largest centre dedicated to improving children's health. Our commitment is to improve the health of children, here in Canada and in the global community. SickKids is affiliated with the University of Toronto 
 

More than 2,200 scientific staff, trainees and knowledge workers
 

SickKids Research Institute
 

Research activities are coordinated under seven major research programs, which range from basic science at the sub-molecular level, to organ systems, to population health. The seven programs are: Cell Biology, Child Health Evaluative Sciences, Developmental & Stem Cell Biology, Genetics & Genome Biology, Molecular Structure & Function, Neurosciences & Mental Health, and Physiology & Experimental Medicine

237 researchers (2007-2008)
 

• Historical:
  •  
    • Developed and commercialized Pablum - an infant nutritional supplement
    • Discovery of the CF gene
    • Part of the international team that uncovered the human genetic variation, the journal Science's Scientific Breakthrough of the Year for 2007
• Awards & Distinctions:
  • Home to 24 endowed academic chairs, 30 Canada Research Chairs, and two CIHR Scientific Directors
  • Chief of Research Dr. Janet Rossant elected to the US National Academies of Science
  • Dr. Teresa To, program head of Child Health Evaluative Sciences program received the Eminent Scientist of the Year Award 2008 in the field of Pediatrics and Community Health Research, by the International Research Promotion Council (IRPC).
  • Dr. Steve Scherer received the Ontario Premier's Summit award.
  • Dr. Lisa Robinson received the CIHR Synapse award
  • Dr. Stanley Zlotkin was named an international Ashoka fellow
  • Drs. Freda Miller and Michael Salter became Howard Hughes Medical Institute International Research Scholars.
• Recent Discoveries:
  • SickKids researchers have published many research findings in high impact journals on genetic variations associated with kidney failure, new understanding of chronic bacterial infections, structural changes of chromosomes in autism, safety of use of antidepressants in pregnancy, risk of diseases due to climate change, how cancer stem cells hide in tumours, effectiveness of the use of sucrose as pain relief for newborns, strategies for addressing safe drinking water in Bangladesh, novel therapies for chronic back pain, new understanding of learning and memory deficits.

• More than 1,000 funded research projects and approximately 200 research partnerships with pharmaceutical and biotechnology companies
• Established the Induced Pluripotent Stem (iPS) Cell Facility which will develop best practices in the technologies of reprogramming with a focus on the establishment and banking of patient-specific primary fibroblast cell lines, and the subsequent generation and characterization of iPS cells.
• Established the Centre for Pain Management, Research and Education is an innovative leading-edge entity that fosters excellence, integrity, innovation and collaboration amongst clinicians, educators and scientists. The centre enhances children's pain outcomes, professional and consumer education, collaborative clinical and basic science research initiatives and local, national and international leadership. The Pain Centre is one of seven centres at SickKids.
• In order to provide for the wide array of infrastructure requirements of our research community, we are home to a series of specialized scientific core facilities. Each of these facilities provides technical expertise and services as well as access to state-of-the art equipment to our researchers on a cost recovery basis. The Centre for Applied Genomics (TCAG) one of our most active and international known centres provides many services and also hosts the Database of Genomic Variants, (also known as the Toronto database) a curated catalogue of structural variation in the human genome. Other core facilities include SIDNET, the Advanced Bioimaging Centre, the Advancer Protein Technology Centre, the Centre for Computational Biology, the Flow Cytometry Facility, and others.
• Home to the Community Health Systems Resource Group (CHSRG) which is comprised of a group of dedicated health systems scientists who conduct research in many areas important to the well-being and mental health of children. The CHSRG uses an innovative model partnering with community organizations to develop and conduct research, and then share the results to improve the health and well-being of the world's children. The purpose of the CHSRG is to create and implement systemic models for children's success through the transfer of knowledge to all who can influence healthy outcomes for children.
  
  

The Centre for Applied Genomics

Stem Cell Research in the Toronto Region

http://www.sickkids.ca
http://www.sickkids.ca/Research/index.html
http://www.sickkids.ca/Learning/index.html